Kevin G. Keegan
Professor - Equine Surgery

· BS (Agriculture), University of Missouri, Columbia, MO
· BS (Biochemistry), University of Missouri, Columbia, MO
· DVM (Veterinary Medicine), University of Missouri, Columbia, MO
· MS (Veterinary Clinical Sciences), University of Illinois, Urbana, IL

· Diplomate, American College of Veterinary Surgeons (ACVS)

KeeganK@missouri.edu

Research emphasis:

Research projects have focused upon utilizing kinematic analysis to evaluate lameness in horses.  We are performing basic kinematic research and conducting clinical trials utilizing what we have learned. We have developed a telemeterized, accelerometer-based, alternative lameness evaluation technology that can be used in the overground field setting.  We are also investigating novel data mining approaches to data analysis to better accommodate the voluminous data output inherent in kinematic analysis (wavelet preprocessing, neural network classification). These novel data mining approaches may find utility in human sports medicine and rehabilitation fields. We are now collaborating to develop 3D animation program or software that will allow more intuitive analysis of hoof movement. When this sensing system and analysis are perfected, we plan to begin testing present widely accepted (but non-objectively tested) farrier techniques for the manipulation of hoof wall movement in horses. I also collaborate on a project using kinematic analysis to investigate upward fixation of the patella.

Selected publications:

Keegan KG, Messer NT, Reed SK, Wilson DA, Kramer J.  Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses.  Am J Vet Res. 2008; 69(2):167-73. [Abstract]

Keegan KG.  Evidence-based lameness detection and quantification.  Vet Clin North Am Equine Pract. 2007; 23(2):403-23. Review.  [Abstract]

Janicek JC, Keegan KG.  What is your diagnosis? Subluxation of DIPJ.  J Am Vet Med Assoc 2007; 230(9):1307-8. [No abstract available.]

Reed SK, Messer NT, Tessman RK, Keegan KG.  Effects of phenylbutazone alone or in combination with flunixin meglumine on blood protein concentrations in horses.  Am J Vet Res 2006; 67(3):398-402. [Abstract]

Keegan KG, Satterley JM, Skubic M, Yonezawa Y, Cooley JM, Wilson DA, Kramer J.  Use of gyroscopic sensors for objective evaluation of trimming and shoeing to alter time between heel and toe lift-off at end of the stance phase in horses walking and trotting on a treadmill.  Am J Vet Res 2005; 66(12):2046-54. [Abstract]

Garcia-Seco E, Wilson DA, Cook JL, Kuroki K, Kreeger JM, Keegan KG.  Measurement of articular cartilage stiffness of the femoropatellar, tarsocrural, and metatarsophalangeal joints in horses and comparison with biochemical data. Vet Surg 2005; 34(6):571-78. [Abstract]

Kelmer G, Keegan KG, Kramer J, Wilson DA, Pai FP, Singh P.  Computer-assisted kinematic evaluation of induced compensatory movements resembling lameness in horses trotting on a treadmill. Am J Vet Res 2005; 66(4):646-55. [Abstract]

Garcia-Seco E, Wilson DA, Kramer J, Keegan KG, Branson KR, Johnson PJ, Tyler JW.  Prevalence and risk factors associated with outcome of surgical removal of pedunculated lipomas in horses: 102 cases (1987-2002).  J Am Vet Med Assoc 2005; 226(9):1529-37. [Abstract]

Keegan KG, Arafat S, Skubic M, Wilson DA, Kramer J, Messer NM, Johnson PJ, O'Brien DP, Johnson G.  Detection of spinal ataxia in horses using fuzzy clustering of body position uncertainty. Equine Vet J  2004; 36(8):712-17. [Abstract]

Kramer J, Keegan KG, Kelmer G, Wilson DA.  Objective determination of pelvic movement during hind limb lameness by use of a signal decomposition method and pelvic height differences.  Am J Vet Res 2004; 65(6):741-47. [Abstract]

Keegan KG, Yonezawa Y, Pai PF, Wilson DA, Kramer J.  Evaluation of a sensor-based system of motion analysis for detection and quantification of forelimb and hind limb lameness in horses.  Am J Vet Res 65(5):665-70, 2004.  [Abstract]

Kramer J, Keegan KG, Kelmer G, Wilson DA. Objective determination of pelvic movement during hindlimb lameness using a signal decomposition method and pelvic height differences. Am J Vet Res 65(6):741-47, 2004.  [Abstract]

Keegan KG, Arafat S, Skubic M, Wilson DA, Kramer J.  Detection of lameness and determination of the affected forelimb in horses by use of continuous wavelet transformation and neural network classification of kinematic data.  Am J Vet Res 64(11):1376-381, 2003. [Abstract]

Templer AS, Garcia-Seco E, Johnson PJ, Keegan KG, Lattimer JC.  Use of abdominal ultrasonography for the characterization of strangulating jejunal obstruction associated with peduculated lipomas.  Equine Vet Educ J 15(1):52-55, 2003.

Keegan KG, Yonezawa Y, Pai PF, Wilson DA.  Accelerometer-based system for the detection of lameness in horses. Biomed Sci Instrumen 38:107-112, 2002.  [Abstract]

Schwartz AJ, Wilson DA, Keegan KG, Ganjam VK, Sun Y, Weber KT, Zhang J.  Factors regulating collagen synthesis and degradation during second-intention healing of wounds in the thoracic region and the distal aspect of the forelimb of horses.  Am J Vet Res 63(11):1564-70, 2002. [Abstract].

Keegan KG, Pai PF, Wilson DA, Smith BK.  Signal decomposition method of evaluating head movement to measure induced forelimb lameness in horses trotting on a treadmill. Equine Vet J 33(5):446-451, 2001.  [Abstract]

Bacon Miller C, Wilson DA, Keegan KG, Kreeger JM, Adelstein EH, Ganjam VK. Growth characteristics of fibroblasts isolated from the trunk and distal aspect of the limb of horses and ponies. Vet Surg 29:1-7, 2000.  [Abstract]

Keegan KG, Wilson DA, Smith BK, Wilson DJ.  Changes in kinematic variables seen with lameness induced by applying pressure to the frog and to the toe in adult horses trotting on a treadmill. Am J Vet Res 61:612-619, 2000.  [Abstract]

Kramer J, Keegan KG, Wilson DA, Smith BK, Wilson DJ.  Kinematics of the equine hindlimb in trotting horses after induced distal tarsal lameness and distal tarsal anesthesia. Am J Vet Res 61:1031-1036, 2000.  [Abstract]

Keegan KG, Pai PF, Wilson DA, Smith BK.  A curve-fitting technique for evaluating head movement to measure forelimb lameness in horses. Biomed Sci Instrumen 36:239-244, 2000. [Abstract]

Kellam LL, Johnson PJ, Kramer J, Keegan KG.  Gastric impaction and obstruction of the small intestinal associated with persimmon phytobezoar in a horse. J Am Vet Med Assoc 216:1279-1281, 2000.  [Abstract]

Johnson PJ, Wilson DA, Keegan KG, Purcell KL, Moore LA, Kreeger JM, Frankeny RL, Lattimer JC.  Retrospective study of cecocolic intussusception (cecal inversion) in 9 horses (1982-1998). J Equine Vet Sci 19(3):190-195, 1999.  

Wilson DA, Keegan KG, Carson WA. An in vitro biomechanical comparison of two fixation methods for transverse osteotomies of the medial proximal forelimb sesamoid bones in horses. Vet Surg 28:355-367, 1999.  [Abstract]

Frankeny RL, Wilson DA, Keegan KG.  An in vitro biomechanical investigation of compression plating with cable cerclage for repair of oblique osteotomies in foal femurs. Vet Comp Orth Traum 11:23-28, 1998.  

Keegan KG, Wilson DJ, Wilson DA, Barnett CD, Smith B.  Effects of balancing and shoeing of the forelimb feet on kinematic gait analysis in 5 horses with navicular disease. J Equine Vet Sci 18:522-527, 1998.

Keegan KG, Wilson DA, Wilson DJ, Smith B, Gaughan EM, Pleasant RS, Lillich JD, Kramer J, Howard RD, Bacon-Miller C, Davis EG, May KA, Cheramie HS, Valentino WL, van Harrevald PD.  Evaluation of mild lameness in horses trotting on a treadmill: Agreement by clinicians and interns or residents and correlation of their assessments with kinematic gait analysis. Am J Vet Res 59:1370-1377, 1998.  [Abstract]

Keegan KG, Wilson DJ, Wilson DA, Frankeny RL, Loch WE, Smith B.  Effects of anesthesia of the palmar digital nerves on kinematic gait analysis in horses with and without navicular disease. Am J Vet Res 58:218-223, 1997.  [Abstract]

Aronoff N, Keegan KG, Johnson PJ, Wilson DA, Reed AL.  Management of pyloric obstruction in a foal. J Am Vet Med Assoc 210:902-905, 1997.  [Abstract]

Matthews GL, Keegan KG, Graham HL.  Effects of tendon grip technique (frozen vs unfrozen) on in vitro surface strain measurements of the equine deep digital flexor tendon. Am J Vet Res 57:111-115, 1996.  [Abstract]

Keegan KG, Wilson DA, Kreeger JM, Ellersieck MR, Kuo KC, Li Z.  Local distribution of mepivacaine following distal interphlangeal joint injection in the horse. Am J Vet Res 57:422-426, 1996.  [Abstract]

Keegan KG, Wilson DA, Lattimer JC, Twardock AR, Ellersieck MR.  Scintigraphic evaluation of 99mTc-methylene diphosphonte uptake in the navicular area of horses with lameness isolated to the foot by anesthesia of the palmar digital nerves. Am J Vet Res 57:415-421, 1996.  [Abstract]

Wilson DA, Adelstein EH, Keegan KG, Barrett BA, Kutz RR Jr.  In-vitro and in-vivo effects of activated macrophage supernatant on distal limb wound of ponies. Am J Vet Res 57:1220-1224, 1996.  [Abstract]

Keegan KG, Dillavou CL, Turnquist SE, Fales WH.  Subcutaneous mycetoma-like granuloma in a mare caused by Aspergillus versicolor. J Vet Diag Invest 7:564-567, 1995.  [Abstract]

Frankeny RL, Johnson PJ, Messer NT, IV, Keegan KG, Corwin LA, Jr.  Bilateral tibial metaphyseal stress fractures associated with physitis in a foal. J Am Vet Med Assoc 205:76-78, 1994.  [Abstract]

Keegan KG, Twardock AR, Losonsky JM, Baker GJ.  Scintigraphic evaluation of fractures of the distal phalanx in horses-27 cases (1979-1988). J Am Vet Med Assoc 202:1993-1997, 1993.  [Abstract]

Turnquist SE, Pace LW, Keegan KG, Andrews-Jones L, Kreeger JM, Bailey KL, Stogsdill PL, Wilson HA.  Botryoid rhabdomyosarcoma of the urinary bladder in a filly. J Vet Diagn Invest 5:451-453, 1993.  [Abstract]

Keegan KG, Baker GJ, Boero MJ, Pijanowski GJ, Phillips JW.  Evaluation of support bandaging during measurement of proximal sesamoidean ligament strain in horses by use of a mercury strain gauge. Am J Vet Res 53:1203-1208, 1992.  [Abstract]

Goetz TE, Ogilvie GK, Keegan KG, Johnson PJ, Lerner D.  Cimetidine for treatment of melanomas in three horses. J Am Vet Med Assoc 196:449-452, 1990.  [Abstract]

Goetz TE, Holland CJ, Dawson JE, Ristic M, Skibbe K,Keegan KG, Johnson PJ, Schaeffer DJ, Baker GJ.  Monthly prevalence (in 1986) of antibody titers against equine monocytic Ehrlichiosis in apparently healthy horses in Illinois. Am J Vet Res 50:1936-39, 1989.  [Abstract]